Stories about: Dr. Leslie Smoot

Chloe’s smile: Moving the needle on Williams syndrome research

Chloe is cared for at the Boston Children's Williams Syndrome Clinic.
“Because of your smile, you make life more beautiful.” ~ Thich Nhat Hanh

Her wide, warm smiles are generous. Even strangers can’t resist smiling back. “Chloe loves people and relationships,” says her mom, Johanna. “She can completely change a person’s demeanor with one of her incredible smiles.”

Now, Chloe’s powerful smile is bringing together supporters and scientists to advance research on Williams syndrome, the rare neurodevelopmental disorder she was born with 11 years ago.

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Kalev’s story: Advances in medical management of pediatric heart failure

Kalev-11In recent years, the Boston Children’s Hospital Heart Failure team has made significant strides in slowing the progress of heart failure in children. In some cases, disease progression has been slowed enough for the patient to be taken off of the heart transplant list for being “too well.”

The following is part three of a four-part series featuring Heart Center patients who were once listed for transplant but were removed thanks to successful medical management of his or her heart disease.

Searching for answers

This story is part of a four part series on patients who were taken off the heart transplant list thanks to medical management. Read the entire series here.

Thirty weeks into her second pregnancy, Katie Rosenthal just felt like something was wrong. She asked her obstetrician for another ultrasound and soon discovered that her unborn baby’s heart was in serious danger.

Almost immediately, Katie was admitted to a large hospital close to home in Colorado. The fetal cardiologists weren’t exactly sure what they were dealing with but decided to place Katie on an extremely high dose of digoxin in the hopes that the drug would get to her unborn child’s heart and help it contract.

After spending four days at the hospital, Katie and her husband Eric decided they needed a more conclusive diagnosis regarding what was really wrong with their baby’s heart. They went to another hospital in Colorado and received a new diagnosis. Confused, anxious and determined to do what was best for their child, the Rosenthals asked family friends in the medical field as well as their pediatrician: “What would you do if it was your child?”

“They all said, ‘Go to Boston,’” says Katie.

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