Avery Toole is 12. She’s an only child — with three older brothers.
Dalton and Avery’s lives intersected in 2009.
Dalton was riding his bike, while on a family vacation.
Avery, 5, was at Boston Children’s Hospital, her life hanging in the balance. She had been on the transplant list, waiting for a heart for 52 days.
Dalton was struck by a truck.
One week after the accident, Dr. Elizabeth Blume, medical director of the Boston Children’s Heart Transplant Program, phoned Avery’s parents Cheryl and Mike Toole. She had “the perfect heart” for Avery.
“We knew Dalton didn’t need his organs wherever he was going,” says Dalton’s father Jim Lawyer. Jim, an anesthesiologist, and his wife Jeri, an operating room nurse, donated their son’s organs.
Avery’s heart transplant
The 18-hour surgery to transplant Dalton’s heart into Avery’s chest was a success.
It changed Avery’s life.
Avery had been in and out of Boston Children’s since birth when she was diagnosed with hypoplastic left heart syndrome (HLHS), a very serious congenital heart defect in which the left side of the heart is underdeveloped and can’t pump enough red blood to supply the body.
“Avery is our only child. Even though we normalized life in her early years, it was so hard,” says her mother Cheryl Toole, nursing director of the Boston Children’s Neonatal Intensive Care Unit.
Avery had eight open-heart surgeries. Her skin was tinged blue because her oxygen levels were chronically low. Normal childhood activities like going to a birthday party were exhausting.
At age 4, her heart was failing. She was being kept alive by a Berlin Heart, an external device to mechanically pump her blood.
“Her heart transplant turned her life around in ways we expected and in ways we never anticipated,” says Cheryl.
Avery: After her heart transplant
No longer a chronic patient, Avery is an active 12-year-old who plays lacrosse, soccer and basketball. These are the clinical outcomes everyone hoped for. “Looking at Avery today, you’d never know what she’s been through,” says Cheryl.
Avery’s heart transplant also brought some unimagined changes into the Toole’s lives. After her transplant, they sent a letter to the organ bank to thank the donor’s family. It made its way to the Lawyers. The families agreed to meet and bonded in a way none of them expected. They have become family, vacationing together every year and sharing and creating memories.
Avery has an incredible heart and is in great health. Dalton’s brothers have become her brothers. The Lawyers find some comfort, knowing their son’s heart beats strong in Avery’s chest. “Because of Dalton, Avery has a chance,” says Jim.
On August 31, Avery started middle school. “It’s another milestone Mike and I never thought we would have the fortune to celebrate,” says Cheryl.
Be part of the greatest children’s stories ever told. Share your story.
Research and innovation: Making pediatric heart transplants possible
Though Dalton’s blood and tissue types were perfect matches for Avery, she had antibodies that made her heart transplant especially challenging. Avery had had so many transfusions during her young life, her immune system had developed antibodies to fight off what it perceived as risks – from donated blood or a donated organ.
An adult who had developed a similar level of antibodies would have been removed from the transplant list because the risk of rejection would be too high.
Specialists in the Boston Children’s Heart Transplant Program, in collaboration with other leaders in pediatric heart transplant, had developed specialized pediatric protocols, including high-dose steroids and other medications, to help clear those antibodies and reduce the risk of rejection.
After Avery’s transplant she underwent a number additional procedures to keep the amount of circulating antibodies at a safe level and minimize the risk of rejection. The heart transplant and extended treatment succeeded, making it possible for Avery’s young body to accept and thrive with Dalton’s heart.
Learn more about the Boston Children’s Heart Transplant Program.